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Article

Molecular evidence for a clonal relationship between synchronous uterine endometrioid carcinoma and ovarian clear cell carcinoma: a new example of "precursor escape"?

Journal of molecular medicine (Berlin, Germany) - 1 Jul 2021

Weng Cindy Hsuan, Wu Ren-Chin, Chen Shu-Jen, Chen Hua-Chien, Tan Kien Thiam, Lee Yun-Shien, Huang Shih-Sin, Yang Lan-Yan, Wang Chin-Jung, Chou Hung-Hsueh, Chao An-Shine, Chao Angel, Lai Chyong-Huey

Abstract excerpt

Synchronous endometrial and ovarian carcinomas (SEOCs) that share the same endometrioid histology are generally considered as the result of metastatic spread from one organ to another. However, SEOCs with different histologies are regarded as distinct primary lesions that arise independently from each other. This study was undertaken to compare the mutational landscape of SEOCs with different histologies to...

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Share to Adenocarcinoma, Clear Cell
Share to Carcinoma, Endometrioid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Endometrial Neoplasms

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Identifiers

PMID: 33768299
DOI: 10.1007/s00109-021-02064-4

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