Transcriptome Profiling and Network Analysis Provide Insights Into the Pathogenesis of Vulvar Lichen Sclerosus

Abstract excerpt

Vulvar lichen sclerosus (VLS) is a chronic inflammatory dermatosis that affects female anogenital skin. Although VLS is considered a T cell-mediated autoimmune disease, the diagnosis criteria, molecular mechanism, and universally accepted therapies for this disease remain largely unresolved. To explore disease pathogenesis and potential biomarkers, we performed an RNA-Seq-based transcriptome analysis to profile...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genital Health and Disease
• Share to Musculoskeletal synovial abnormalities and treatments
• Share to Urologic and reproductive health conditions