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Dysregulation of Glucose Metabolism by Oncogenes and Tumor Suppressors in Cancer Cells

26 Sept 2018

Abstract excerpt

Cancers are complex diseases having several unique features, commonly described as ‘hallmarks of cancer’. Among them, altered signaling pathways are the common characteristic features that drive cancer progression; this is achieved due to mutations that lead to the activation of growth promoting(s) oncogenes and inactivation of tumor suppressors. As a result of which, cancer cells increase their glycolytic rate...

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PMID: 30255690
DOI: 10.22034/apjcp.2018.19.9.2377

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