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Article

Serum sphingosine-1-phosphate levels are associated with brain metastasis in EGFR-mutant lung adenocarcinoma.

Future oncology (London, England) - 1 Sept 2025

Xu Gang, Li Yajie, An Bo, Pan Bo, Shang Lihua, Yu Yan, Jia Dexin

Abstract excerpt

AIM: To investigate the association between serum sphingosine-1-phosphate (S1P) levels and brain metastasis in EGFR-mutant lung adenocarcinoma (LUAD). METHODS: Serum S1P levels were analyzed in 103 LUAD patients. The baseline characteristics of the 103 patients in this study included the following: the overall cohort consisted of 50.49% males and 49.51% females. The average age of the cohort was 69.50 years...

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Identifiers

PMID: 40742314
DOI: 10.1080/14796694.2025.2539059
PMCID: PMC12408039

Genes

EGFR

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