Article
Driver genes as predictive indicators of brain metastasis in patients with advanced NSCLC: EGFR, ALK, and RET gene mutations.
Cancer medicine - 1 Jan 2020
Wang Huijuan, Wang Ziqi, Zhang Guowei, Zhang Mina, Zhang Xiaojuan, Li Haixia, Zheng Xuanxuan, Ma Zhiyong
Abstract excerpt
BACKGROUND: A retrospective analysis verified the role of gene mutations in brain metastasis in patients with non-small cell lung cancer (NSCLC). METHODS: Data from 552 patients with advanced NSCLC treated from January 2015 to June 2017 in the Affiliated Cancer Hospital of Zhengzhou University were retrospectively analyzed. Next-generation sequencing was used to detect mutations in eight reported driver genes and...
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