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Article

The molecular biology of lung cancer brain metastasis: an overview of current comprehensions and future perspectives.

The journal of medical investigation : JMI - 1 Jan 2014

Hanibuchi Masaki, Kim Sun-Jin, Fidler Isaiah J, Nishioka Yasuhiko

Abstract excerpt

Brain metastases occur in 20-40% of patients with advanced malignancies and lung cancer is one of the most common causes of brain metastases. The occurrence of brain metastases is associated with poor prognosis and high morbidity in patients with advanced lung cancer, even after intensive multimodal therapy. Progress in treating brain metastases has been hampered by a lack of model systems, a lack of human tissue...

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PMID: 25264041
DOI: 10.2152/jmi.61.241

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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