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Epigenomic signatures of accelerated epigenetic aging are associated with congenital heart disease in newborns

28 Jul 2025

Abstract excerpt

BACKGROUND: Congenital heart disease (CHD) lesions are the most common birth defects and despite advances in care, are associated with short- and long-term co-morbidities. The exact mechanisms that may influence outcomes in survivors with CHD remain unclear and are likely multi-factorial; exploring the epigenome in these cases may provide novel insights into predictive biomarkers contributing to outcomes. The...

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PMID: 40722095
DOI: 10.1186/s12920-025-02189-2

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