Article
Multiomic Investigation of Shared Genetic Pathways in Paediatric Congenital Heart Disease and Neurodevelopmental Disorders.
Human mutation - 1 Jan 2026
Thompson Jamie-Lee M, Gao Yunkai, Iwasawa Eri, Das Debjani, Rath Emma, Troup Michael, Humphreys David T, Heydarian Haleh, Anixt Julia, Kasparian Nadine A, Froehlich Tanya E, Tchieu Jason, Weaver K Nicole, Congenital Heart Disease Synergy Study Group, Kirk Edwin P, Dale Russell, Dunwoodie Sally L, Winlaw David S, Giannoulatou Eleni
Abstract excerpt
Recent medical advances have significantly improved the life expectancy of individuals with congenital heart disease (CHD); however, these children remain at increased risk of co-occurring neurodevelopmental disorders (NDD), such as attention-deficit/hyperactivity disorder and autism spectrum disorder. Although prenatal environmental factors, including placental dysfunction and altered oxygen levels in utero, as...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.