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Maternal Genome-Wide DNA Methylation Patterns and Congenital Heart Defects

24 Jan 2011

Abstract excerpt

The majority of congenital heart defects (CHDs) are thought to result from the interaction between multiple genetic, epigenetic, environmental, and lifestyle factors. Epigenetic mechanisms are attractive targets in the study of complex diseases because they may be altered by environmental factors and dietary interventions. We conducted a population based, case-control study of genome-wide maternal DNA methylation...

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PMID: 21297937
DOI: 10.1371/journal.pone.0016506

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