Inchworm migration facilitates amoeboid cell adaptation to high-adhesion environments

Abstract excerpt

Cells dynamically adapt their migration modes to environmental conditions, but their response to sticky surfaces, where they risk becoming immobilized, remains unclear. In our study, we discovered that strong adhesion prompts substantial changes in Dictyostelium discoideum, leading to "inchworm migration," a novel subtype of amoeboid migration. This adaptation involves minimal contact between the cell and the...

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