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A Mutant of Dictyostelium discoideum, KI-Cell, as a Model of Collective Cell Migration Independent of Chemotaxis.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2024

Hayakawa Masayuki, Kuwayama Hidekazu, Shibata Tatsuo

Abstract excerpt

Collective cell migration occurs when the orientation of cell polarity is aligned with each other in a group of cells. Such collective polarization depends on a reciprocal process between cell intrinsic mechanisms such as cell-cell adhesion and extracellular guidance mechanism such as wound healing and chemotaxis. As part of its development life cycle, individual single cells of Dictyostelium discoideum exhibit...

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PMID: 39147968
DOI: 10.1007/978-1-0716-4023-4_4

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