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Article

A flagellate-to-amoeboid switch in the closest living relatives of animals.

eLife - 15 Jan 2021

Brunet Thibaut, Albert Marvin, Roman William, Coyle Maxwell C, Spitzer Danielle C, King Nicole

Abstract excerpt

Amoeboid cell types are fundamental to animal biology and broadly distributed across animal diversity, but their evolutionary origin is unclear. The closest living relatives of animals, the choanoflagellates, display a polarized cell architecture (with an apical flagellum encircled by microvilli) that resembles that of epithelial cells and suggests homology, but this architecture differs strikingly from the...

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Identifiers

PMID: 33448265
DOI: 10.7554/eLife.61037
PMCID: PMC7895527

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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