Article

Type-IV pili tune an adhesion-migration trade-off during surface colonization of <i>Pseudomonas aeruginosa</i>

2023-05-09

Abstract excerpt

Bacterial pathogenicity relies on both firm surface adhesion and cell dissemination. How twitching bacteria resolve the fundamental contradiction between adhesion and migration is unknown. To address this question, we employ live-cell imaging of type-IV pili (T4P) and therewith construct a comprehensive mathematical model of Pseudomonas aeruginosa migration. The data show that only 10% to 50% of T4P bind to subst...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1d880194-b48a-5d8d-b628-2c5cd731bbfd
DOI: 10.1101/2023.05.09.538458

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Type-IV pili tune an adhesion-migration trade-off during surface colonization of <i>Pseudomonas aeruginosa</i>DOI 10.1101/2023.05.09.538458Read

Substrate stiffness impacts early biofilm formation by modulating <i>Pseudomonas aeruginosa</i> twitching motilitySemantic proximity Read

Bacteria use type IV pili to walk upright and detach from surfaces.Semantic proximity Read

<i>Pseudomonas aeruginosa</i> balances cytotoxicity and motility to counter phagocytosis by macrophagesSemantic proximity Read

Type IV pilus length determines virulence by regulating a hidden subpopulation of non-contributing filamentsSemantic proximity Read

Type IV pili mechanochemically regulate virulence factors in Pseudomonas aeruginosa.Semantic proximity Read

Bacterial motility: how do pili pull?Semantic proximity Read

Bacteria use type-IV pili to slingshot on surfaces.Semantic proximity Read

Delayed onset and heterogeneous collective organization characterize twitching motility in <i>Acinetobacter baumannii</i>Semantic proximity Read

How Bacteria Use Type IV Pili Machinery on Surfaces.Semantic proximity Read

Nanoscale Pulling of Type IV Pili Reveals Their Flexibility and Adhesion to Surfaces over Extended Lengths of the Pili.Semantic proximity Read

Separation of Pseudomonas aeruginosa type IV pilus-dependent twitching motility and surface-sensing responses.Semantic proximity Read

Bacteria as living patchy colloids: Phenotypic heterogeneity in surface adhesion.Semantic proximity Read