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Article

Persistent infection and associated nucleotide changes of West Nile virus serially passaged in hamsters.

The Journal of general virology - 1 Dec 2008

Wu Xiaoyan, Lu Liang, Guzman Hilda, Tesh Robert B, Xiao Shu-Yuan

Abstract excerpt

Hamsters experimentally infected with the neuroinvasive West Nile virus (WNV) strain NY385-99 frequently develop persistent renal infection and viruria. Viruses recovered from the urine of such animals no longer cause neurological disease when inoculated into naïve hamsters. To examine if this phenotypic change is stable, and if additional nucleotide changes occur during further passages, a urine isolate from a...

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PMID: 19008395
DOI: 10.1099/vir.0.2008/003210-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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