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Article

Life's Crucial 9, Genetic Susceptibility, and the Risk of Atrial Fibrillation: A Prospective Study in the UK Biobank Cohort.

The Canadian journal of cardiology - 1 Apr 2026

Li Jianing, Li Guoxian, Ma Ze, Sun Ziqing, Shi Yujie, Lou Zexin, Zhao Hanqing, Sun Mengtong, Wang Yu, Han Qiang, Jiang Miao, Shen Yueping

Abstract excerpt

BACKGROUND: To date, the association between Life's Crucial 9 (LC9) and incidence of atrial fibrillation (AF) has not been explored. This study aimed to investigate the association between LC9 and the incidence of AF and evaluate the potential role of genetic risk. METHODS: LC9 consists of 9 elements categorized as low, medium, and high cardiovascular health (CVH). Polygenic risk scores (PRSs) were categorized as...

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PMID: 40692006
DOI: 10.1016/j.cjca.2025.07.021

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