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Article

Cardiovascular Health, Genetic Susceptibility, and the Risk of Incident Autoimmune Disorders in the UK Biobank: A Prospective Cohort Study.

Journal of the American Heart Association - 20 May 2025

Lin Lijin, Shan Yuanjun, Lei Fang, Zhang Jianqing, Zhang Li, Zhang Xiao-Jing, Yao Wenlin, She Zhi-Gang, Li Hongliang

Abstract excerpt

BACKGROUND: Autoimmune diseases are closely linked to cardiovascular diseases. This study aimed to assess the relationship between cardiovascular health (CVH) defined by Life's Essential 8 (LE8), genetic predisposition, and the risk of 19 autoimmune disorders. METHODS AND RESULTS: A total of 247 660 participants without prior autoimmune diseases from the UK Biobank were included. CVH was assessed using LE8...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40371604
DOI: 10.1161/JAHA.124.039451
PMCID: PMC12184553

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