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Deciphering cancer therapy resistance via patient-level single-cell transcriptomics with CellResDB

15 Jul 2025

Abstract excerpt

Cancer therapy resistance remains a major challenge, with limited resources available for systematically studying its underlying mechanisms at the patient level. The existing databases are either restricted to bulk RNA-seq data, lack single-cell resolution, or provide limited clinical annotations, making them insufficient for in-depth exploration of the tumor microenvironment (TME) dynamics in therapy resistance....

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PMID: 40664938
DOI: 10.1038/s42003-025-08457-2

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