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Article

Transcriptomic mortality signature defines high-risk neonatal sepsis endotype

27 Jun 2025

Abstract excerpt

Introduction: Neonatal sepsis remains a leading cause of global childhood mortality, yet treatment options are limited. Clinical and biological heterogeneity hinders the development of targeted therapies. Gene-expression profiling offers a potential strategy to identify neonatal sepsis subtypes and guide targeted intervention. Methods: We performed secondary analyses of publicly available gene-expression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40655143
DOI: 10.3389/fimmu.2025.1601316

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