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SRSF7 promotes pulmonary fibrosis through regulating PKM alternative splicing in lung fibroblasts

22 Apr 2025

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF), a chronic interstitial lung disease , is characterized by aberrant wound healing , excessive scarring and the formation of myofibroblastic foci. Although the role of alternative splicing (AS) in the pathogenesis of organ fibrosis has garnered increasing attention, its specific contribution to pulmonary fibrosis remains incompletely understood. In this study, we identified an...

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PMID: 40654335
DOI: 10.1016/j.apsb.2025.04.017

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