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Antibacterial Activity of Non-Biaryl-Linked Dimeric Tetraxanthones: Insights into Stability and Efficacy against Gram-Positive Bacteria

14 Jul 2025

Abstract excerpt

Aflaxanthone B ( 1 ), a non-biaryl-linked dimeric tetraxanthone, was purified from the endophytic fungus Preussia sp. CPCC 401464. Four undescribed transformed products, aflaxanthones C–F ( 2–5 ), were obtained by treating compound 1 with dimethyl sulfoxide (DMSO). Their structures were determined by analysis of 1D and 2D NMR spectroscopic data as well as HRESIMS analyses. The absolute configuration of these...

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PMID: 40653753
DOI: 10.1021/acs.jnatprod.5c00624

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