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Polycyclic Tetramate Macrolactams—A Group of Natural Bioactive Metallophores

12 Nov 2021

Abstract excerpt

New infectious diseases and increase in drug-resistant microbial pathogens emphasize the need for antibiotics with novel mode-of-action. Tetramates represented by fungi-derived tenuazonic acid and bacterial polycyclic tetramate macrolactams (PTMs) are an important family of natural products with a broad spectrum of antimicrobial activities. Despite their potential application as new antibiotics, it remains...

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PMID: 34869220
DOI: 10.3389/fchem.2021.772858

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