Article
Bioactive derivatives of isopropylstilbene from mutasynthesis and chemical synthesis.
Chembiochem : a European journal of chemical biology - 15 Dec 2014
Kronenwerth Max, Brachmann Alexander O, Kaiser Marcel, Bode Helge B
Abstract excerpt
Isopropylstilbene is a natural product from Photorhabdus luminescens TT01, with multiple biological activities. A mutant deficient in the production of both anthraquinones and cinnamic acid was constructed, thus giving a clean background according to UV detection. This anthraquinone and stilbene deficient (ASD) mutant was used in mutasynthesis experiments to obtain new stilbene derivatives, which were detected by...
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