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Article

Genetically predicted serum urate and cancer risk: a Mendelian randomization study.

Scandinavian journal of rheumatology - 1 Nov 2025

Fatima T, Dehlin M, Burgess S, Mason A M, Nilsson P M, Melander O, Jacobsson Lth, Kapetanovic M C

Abstract excerpt

OBJECTIVE: To evaluate the causal effect of genetically predicted serum urate (SU) levels on the risk of overall and major site-specific cancers in individuals of European ancestry, using Mendelian randomization (MR) analysis. METHOD: Data from two population-based cohorts from southern Sweden, the Malmö Diet and Cancer Study (MDCS) and Malmö Preventive Project (MPP), and summary-statistics data from the Global...

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Identifiers

PMID: 40583621
DOI: 10.1080/03009742.2025.2512667
PMCID: PMC7618153

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