Article
Altered Levels of miRNA-1290 and lncRNA-H19 in Exosomes of Patients Recently Diagnosed With Acute Lymphoblastic Leukemia
27 Jun 2025
Abstract excerpt
Background/Aim: Acute lymphoblastic leukemia (ALL) is a common childhood cancer characterized by high levels of blasts in the bone marrow, and it is influenced by genetic and microenvironmental factors. Genetic variants of the enzyme arylamine N-acetyltransferases 1 (NAT1), regulated by microRNA (miRNA) and long noncoding RNA (lncRNA), have been associated with predisposition to ALL. This study analyzed the...
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