Article
Silencing of Exosomal miR-181a reverses Pediatric Acute Lymphocytic Leukemia Cell Proliferation
2020-05-10
Abstract excerpt
Exosomes are cell-generated nano-vesicles (30-150 nm) found in most biological fluids. Major components of their cargo are lipids, proteins, RNA, DNA, and non-coding RNAs. Exosomes carry the fingerprint of the parental tumor and as such, may regulate tumor growth, progression and metastasis. We investigated the impact of exosomes on cell proliferation in pediatric acute lymphocytic leukemia and its reversal by sil...
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Identifiers and source
- Literature Corpus work
- d398b870-024d-55cb-98c1-d99fd79cd91a
- DOI
- 10.1101/2020.05.10.086967
