Article
Bidirectional regulation between TORC1 and autophagy in Saccharomyces cerevisiae.
Autophagy - 1 Aug 2011
Shin Chun-Shik, Huh Won-Ki
Abstract excerpt
It has been reported in various model organisms that autophagy and the target of rapamycin complex 1 (TORC1) signaling are strongly involved in eukaryotic cell aging and decreasing TORC1 activity extends longevity by an autophagy-dependent mechanism. Thus, to expand our knowledge of the regulation of eukaryotic cell aging, it is important to understand the relationship between TORC1 signaling and autophagy. Many...
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