Interferon-β and interleukin-6 exert opposing effects on Foxp3 acetylation to control regulatory T cell induction

Abstract excerpt

Cytokines are key soluble signaling molecules that regulate immune responses. With the advent of therapies that selectively target cytokines and cytokine receptors, understanding the molecular mechanisms underpinning how immune cells integrate multiple cytokine signals has become a critical challenge in immunology. However, the pleiotropic nature of cytokines makes it difficult to decipher their precise...

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