Article
FuNTB: a functional network clustering tool for the analysis of genome-wide genetic variants in Mycobacterium tuberculosis.
Bioinformatics (Oxford, England) - 1 Jul 2025
Ramos-García Axel A, Mejía-Ponce Paulina M, Sélem-Mojica Nelly, Santos-Díaz Alejandro, Martínez-Ledesma Emmanuel, Licona-Cassani Cuauhtémoc
Abstract excerpt
MOTIVATION: Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), still claims around 1.25 million lives each year. The growing threat of drug resistance-often driven by single‑nucleotide polymorphisms (SNPs) in Mtb genomes underscores the need for high‑quality genomic data and powerful bioinformatics tools. We present FuNTB, a python‑based pipeline that detects non‑synonymous SNPs in Mtb and builds...
Read the complete abstract on PubMedTopics
- Mycobacterium tuberculosis
- Polymorphism, Single Nucleotide
- Software
- Genome, Bacterial
- Cluster Analysis