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Emerging threats of H5N1 clade 2.3.4.4b: cross-species transmission, pathogenesis, and pandemic risk

25 Jul 2025

Abstract excerpt

H5N1 is a highly pathogenic avian influenza virus (HPAIV) with zoonotic potential, posing a significant risk to animal health, agriculture, and human public health. A particular strain, clade 2.3.4.4b, has spread globally and has been detected in various mammalian species-including cattle and a limited number of human cases-highlighting its potential to spark a pandemic. Investigating this specific clade...

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PMID: 40786608
DOI: 10.3389/fcimb.2025.1625665

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