Article
Association analysis of polymorphisms in the N-methyl-D-aspartate (NMDA) receptor subunit 2B (GRIN2B) gene and tardive dyskinesia in schizophrenia.
Psychiatry research - 3 Dec 2007
Liou Ying-Jay, Wang Ying-Chieh, Chen Jen-Yeu, Bai Ya-Mei, Lin Chao-Cheng, Liao Ding-Lieh, Chen Tzu-Ting, Chen Mao-Liang, Mo Geng-Han, Lai I-Ching
Abstract excerpt
Tardive dyskinesia (TD) is a neurological disorder characterized by irregular, non-rhythmic, choreoathetotic and involuntary movements in single or multiple body regions. Chronic administration of typical antipsychotic agents, which predominantly act on dopamine receptors, implicates the dopamine system in susceptibility to TD. An alternative to this dopaminergic supersensivity hypothesis in understanding the...
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