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Article

Analysis of schizophrenia-associated genetic markers in the HLA region as risk factors for tardive dyskinesia.

Human psychopharmacology - 1 Jul 2024

Wang Ruoyu, Lu Justin Y, Herbert Deanna, Lieberman Jeffrey A, Meltzer Herbert Y, Tiwari Arun K, Remington Gary, Kennedy James L, Zai Clement C

Abstract excerpt

OBJECTIVES: The pathology of Tardive Dyskinesia (TD) has yet to be fully understood, but there have been proposed hypotheses for the cause of this condition. Our team previously reported a possible association of TD with the Complement Component C4 gene in the HLA region. In this study, we explored the HLA region further by examining two previously identified schizophrenia-associated HLA-region single-nucleotide...

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PMID: 38676936
DOI: 10.1002/hup.2898

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