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A nanopore sequencing scheme for MiniHap markers and its application in kinship analysis.

Forensic science international. Genetics - 1 Jun 2026

Liu Bo, Zhu Qiang, Jiang Lanrui, Sun Chaoran, Yao Hewen, Zhou Chengye, Wang Chuanxu, Yang Yufei, Wang Xindi, Zhang Zhirui, Zhou Yuxiang, Luo Haibo, Song Feng

Abstract excerpt

Kinship testing based on genetic correlation is one of the primary tasks in forensic genetics. Currently, microhaplotypes (MHs) have become a research hotspot in the field of forensic genetics. Traditional MHs are defined as tightly linked SNPs within short fragments of up to 300 bp. In recent years, nanopore sequencing technology has advanced rapidly. Leveraging its prominent capability for sequencing long...

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PMID: 41965215
DOI: 10.1016/j.fsigen.2026.103501

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