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Article

Implementation of NGS and SNP microarrays in routine forensic practice: opportunities and barriers.

BMC genomics - 28 May 2025

Pedroza Matute Sharlize, Iyavoo Sasitaran

Abstract excerpt

Forensic DNA analysis plays a pivotal role in personal identification, kinship assessment, and criminal investigations, with Short Tandem Repeat (STR) typing via capillary electrophoresis (CE) long established as the gold standard. However, CE-based STR analysis faces notable limitations in multiplexing capacity, the interpretation of degraded or mixed samples, and the resolution of complex kinship relationships....

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PMID: 40437376
DOI: 10.1186/s12864-025-11723-6
PMCID: PMC12117683

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