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Development of a novel microarray data analysis tool without normalization for genotyping degraded forensic DNA.

Forensic science international. Genetics - 1 Jul 2023

Yagasaki Kayoko, Nishida Nao, Mabuchi Akihiko, Tokunaga Katsushi, Fujimoto Akihiro

Abstract excerpt

Since the arrest of the Golden State Killer in the US in April 2018, forensic geneticists have been increasingly interested in the investigative genetic genealogy (IGG) method. While this method has already been in practical use as a powerful tool for criminal investigation, we have yet to know well the limitations and potential risks. In this current study, we performed an evaluation study focusing on degraded...

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PMID: 37137205
DOI: 10.1016/j.fsigen.2023.102885

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