An investigation of downstream processing methods for challenging skeletal samples.

Abstract excerpt

While skeletal remains are known for their resilience and often serve as the final source of information for unidentified human remains (UHRs), the traditional downstream processing of these samples is challenging due to their low template nature, DNA degradation, and the presence of PCR inhibitors, typically resulting in limited probative information. To address this issue, advanced genotyping methods can be...

Topics

• Humans
• Microsatellite Repeats
• Polymorphism, Single Nucleotide
• DNA Fingerprinting
• High-Throughput Nucleotide Sequencing