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Comparison of next generation sequencing (NGS) - (SNPs) and capillary electrophoresis (CE) - (STRs) in the genetic analysis of human remains.

Forensic science international. Genetics - 1 Jan 2025

Kokotas Stavros, Budowle Bruce, Papatheodorou Athanasios, Bolanaki Eugenia, Kondili Aikaterini, Metheniti Aristea, Vouropoulou Maria, Koukouvinos Georgios, Palaigeorgiou Emmanouil, Makras Polyzois

Abstract excerpt

A pilot study was performed using two different DNA technology platforms conducted by two laboratories to analyze DNA extracted from 83-year-old, human male skeletal remains from 16 individuals, of which there are no other viable means to identify these war victims. The workflow of the more recent developed ForenSeq Kintelligence Kit and next generation sequencing was compared to that of the standard capillary...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39241298
DOI: 10.1016/j.fsigen.2024.103131

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