Validation and beyond: Next generation sequencing of forensic casework samples including challenging tissue samples from altered human corpses using the MiSeq FGx system.

Abstract excerpt

The proceeding developments in next generation sequencing (NGS) technologies enable increasing discrimination power for short tandem repeat (STR) analyses and provide new possibilities for human identification. Therefore, the growing relevance and demand in forensic casework display the need for reliable validation studies and experiences with challenging DNA samples. The presented validation of the MiSeq FGx...

Topics

• Cadaver
• DNA
• DNA Fingerprinting
• Forensic Genetics
• Genotype
• High-Throughput Nucleotide Sequencing
• Humans
• Microsatellite Repeats
• Polymorphism, Single Nucleotide
• Reproducibility of Results