Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Berberine treatment inhibits ferroptosis in NIT-1 murine pancreatic cell line via inhibiting OGT expression levels

27 May 2025

Abstract excerpt

Recently, the prevalence of diabetes mellitus (DM) in the world continues to rise, which has seriously threatened human health. Enhanced pancreatic β-cell death is one of the important factors in the pathogenesis of type 1 diabetes mellitus (T1DM). Berberine, an alkaloid, plays a series of pharmacological functions in many disease. The purpose of this study was to explore the specific mechanisms of berberine in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Berberine and alkaloids research
Share to Caveolin-1 and cellular processes
Share to Ferroptosis and cancer prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40425689
DOI: 10.1038/s41598-025-03537-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Berberine treatment inhibits ferroptosis in NIT-1 murine pancreatic cell line via inhibiting OGT expression levelsPMID 40425689Read ↗

Phycocyanin prevents methylglyoxal-induced mitochondrial-dependent apoptosis in INS-1 cells by Nrf2Semantic proximity Read ↗

Role of ferroptosis inhibitors in the management of diabetesSemantic proximity Read ↗

Ferroptosis and iron metabolism in diabetes: Pathogenesis, associated complications, and therapeutic implicationsSemantic proximity Read ↗

Erastin-induced ferroptosis is a regulator for the growth and function of human pancreatic islet-like cell clustersSemantic proximity Read ↗

Protective effect of betanin on cadmium-induced toxicity in MRC-5 cellsSemantic proximity Read ↗

Mitochondrial dysfunction and pancreatic islet β‑cell failure (Review)Semantic proximity Read ↗

Alpha-Heredin targets CAMKⅡ/DRP1-Mediated mitochondrial fission to trigger ferroptosis in pancreatic ductal adenocarcinomaSemantic proximity Read ↗

Excessive iron accumulation mediated oxidative stress and β-cell dysfunction via perturbations of insulin secretion in MIN6 cellsSemantic proximity Read ↗

Integrated Network Pharmacology and Transcriptomics to Explore the Mechanism of Compound Dihuang Granule (CDG) Protects Dopaminergic Neurons by Regulating the Nrf2/HMOX1 Pathway in the 6-OHDA/MPP+ -Induced Model of Parkinson's DiseaseSemantic proximity Read ↗

TERT/FOXO1 signaling promotes islet β-cell dysfunction in type 2 diabetes mellitus by regulating ATG9A-mediated autophagySemantic proximity Read ↗

Effect of NLRP3 gene knockdown on pyroptosis and ferroptosis in diabetic cardiomyopathy injurySemantic proximity Read ↗

PINK1 Mediated Mitophagy Attenuates Early Apoptosis of Gingival Epithelial Cells Induced by High GlucoseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.