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Article

Erastin-induced ferroptosis is a regulator for the growth and function of human pancreatic islet-like cell clusters

7 Sept 2020

Abstract excerpt

Ferroptosis is a newly identified and novel form of cell death, which is characterized by an iron- and reactive oxygen species (ROS)-dependent manner. Potential utility of ferroptotic cell death has been recently proposed for cancer treatment. Meanwhile, ROS generation and apoptosis are inherently consequent to cell apoptosis and dysfunction during islet cell preparation and transplantation. Whether ferroptosis...

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PMID: 32893325
DOI: 10.1186/s13619-020-00055-3

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