Expression of abl and other oncogenes is independent of metastatic potential in Abelson virus-transformed malignant murine large cell lymphoma.

doi:10.1007/BF01758957

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Article

Expression of abl and other oncogenes is independent of metastatic potential in Abelson virus-transformed malignant murine large cell lymphoma.

Clinical & experimental metastasis - 1 Jan 2000

Rotter V, Wolf D, Blick M, Nicolson G L

Abstract excerpt

The role of oncogene expression in tumor metastasis was examined using the Abelson leukemia virus-transformed murine large cell lymphoma RAW117. Cell sublines of low and high metastatic potential expressed equally abl oncogene-coded mRNA and its phosphoprotein product p160, and the capacity of p160 to become autophosphorylated with gamma-[32P]ATP was the same among low and high metastatic cells. The expression of...

Topics

Abelson murine leukemia virus
Animals
Cell Line
Cell Transformation, Neoplastic
Electrophoresis, Polyacrylamide Gel
Female
Gene Expression Regulation
Leukemia, Experimental
Lymphoma
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred BALB C

Neoplasm Metastasis

Oncogenes

Phenotype

Phosphoproteins

RNA, Messenger

RNA, Neoplasm

Source

Open in PubMed

Identifiers

PMID: 4042463
DOI: 10.1007/BF01758957

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-4042463-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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