SAXO proteins mediate tubulin turnover in axonemal microtubules of Chlamydomonas.

doi:10.1242/jcs.264074

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Article

SAXO proteins mediate tubulin turnover in axonemal microtubules of Chlamydomonas.

Journal of cell science - 15 Oct 2025

Zhang Yongli, Li Xuecheng, Wang Zhengmao, Pan Junmin

Abstract excerpt

Cilia and eukaryotic flagella are microtubule-based organelles that are crucial for cell motility and signaling. SAXO proteins (denoted for 'stabilizers of axonemal microtubules') are found exclusively in flagellated or ciliated organisms, but their physiological functions remain unclear. We investigated four SAXO proteins (SAXO1-SAXO4) in Chlamydomonas reinhardtii, identified via bioinformatics. All localize to...

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Source

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Identifiers

PMID: 40421755
DOI: 10.1242/jcs.264074

Genes

SAXO1
SAXO3
SAXO4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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