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Article

A Protocol for Explant Cultures of IDH1-mutant Diffuse Low-grade Gliomas.

Journal of visualized experiments : JoVE - 9 May 2025

Aguilar-Cázarez Kasandra, Pineau Donovan, Garcia Leonor, Huang Guo-Hao, Lv Sheng-Qing, Duffau Hugues, Hugnot Jean-Philippe

Abstract excerpt

Diffuse gliomas, the most prevalent primary brain tumors, are categorized into low and high grades based on histopathological criteria and genetic mutations. Diffuse low-grade gliomas constitute a subset, predominantly afflicting young adults and predisposing to high-grade gliomas. There are two main types of diffuse low-grade gliomas: astrocytomas and oligodendrogliomas, each defined by distinct genetic and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 40418677
DOI: 10.3791/67260

Genes

IDH1
ASCL1
GFAP
OLIG1
OLIG2
SOX9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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