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Article

BDNF gene polymorphisms are associated with Alzheimer's disease-related depression and antidepressant response.

Journal of Alzheimer's disease : JAD - 1 Jan 2011

Zhang Lu, Fang Yu, Zeng Zhaoshu, Lian Yajun, Wei Jianke, Zhu Hongcan, Jia Yanjie, Zhao Xinyu, Xu Yuming

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) is needed to support neuronal survival and differentiation. It also promotes synaptic remodeling and modulates the function of many other neurotransmitters. The current study examined potential association between single nucleotide polymorphisms (SNPs) of the BDNF gene (G11757 C, C270T, G196A, G-712A) and Alzheimer's disease-related depression (AD-D). Participants included...

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Source

Identifiers

PMID: 21677379
DOI: 10.3233/JAD-2011-110113

Genes

BDNF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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