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Genomics of Suicidal Behaviors: What Can We Learn from Polygenic Scores?

The Psychiatric clinics of North America - 1 Jun 2025

Martínez-Levy Gabriela Ariadna, Cruz-Fuentes Carlos Sabás, Sanabrais-Jiménez Marco Antonio

Abstract excerpt

Substantial evidence supports the role of genetic factors in suicide behaviors (SBs). The most recent and powered genome-wide association studies identified significant loci for suicide, suicide attempts, and suicide ideation. Nonetheless, more research is needed to fully understand its impact. A novel approach considering the genetic complexity of SBs is polygenic scores that, in conjunction with individual and...

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PMID: 40348426
DOI: 10.1016/j.psc.2025.01.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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