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Article

Mapping the genetic landscape of suicide risk: Insights from genomic SEM.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics - 1 Jan 2026

Yao Kaifang, Zhuo Chuanjun, Chen Ximing, Li Chao, Song Haitao, Zou Jiatong, Tian Hongjun

Abstract excerpt

The genetic basis of traits associated with suicide risk remains poorly understood. We applied genomic structural equation modeling and integrated multiple post-genome-wide association study (GWAS) analysis strategies to identify potential causal single-nucleotide polymorphisms independent of known high-risk suicide syndrome GWAS variants, identifying four genome-wide-significant, putatively causal loci and six...

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Share to Genetic Predisposition to Disease
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41720715
DOI: 10.1016/j.neurot.2026.e00852
PMCID: PMC12976558

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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