Distinguishing clinical and genetic risk factors for suicidal ideation and behavior in a diverse hospital population.

doi:10.1038/s41398-025-03287-6

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Article

Distinguishing clinical and genetic risk factors for suicidal ideation and behavior in a diverse hospital population.

Translational psychiatry - 20 Feb 2025

Colbert Sarah M C, Lepow Lauren, Fennessy Brian, Iwata Nakao, Ikeda Masashi, Saito Takeo, Terao Chikashi, Preuss Michael, Pathak Jyotishman, Mann J John, Coon Hilary, Mullins Niamh

Abstract excerpt

Suicidal ideation (SI) and behavior (SB) are major public health concerns, but risk factors for their development and progression are poorly understood. We used ICD codes and a natural language processing algorithm to identify individuals in a hospital biobank with SI-only, SB, and controls without either. We compared the profiles of SB and SI-only patients to controls, and each other, using phenome-wide...

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Topics

Humans
Suicidal Ideation
Risk Factors
Male
Female
Middle Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Suicide, Attempted

Adult

Mental Disorders

Multifactorial Inheritance

Genome-Wide Association Study

Genetic Predisposition to Disease

Aged

Case-Control Studies

Source

Open in PubMed Open full text

Identifiers

PMID: 39979244
DOI: 10.1038/s41398-025-03287-6
PMCID: PMC11842747

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