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Article

Functional and molecular characterization of suicidality factors using phenotypic and genome-wide data.

Molecular psychiatry - 1 Mar 2023

Quintero Reis Andrea, Newton Brendan A, Kessler Ronald, Polimanti Renato, Wendt Frank R

Abstract excerpt

Genome-wide association studies (GWAS) of suicidal thoughts and behaviors support the existence of genetic contributions. Continuous measures of psychiatric disorder symptom severity can sometimes model polygenic risk better than binarized definitions. We compared two severity measures of suicidal thoughts and behaviors at the molecular and functional levels using genome-wide data. We used summary association...

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Identifiers

PMID: 36604601
DOI: 10.1038/s41380-022-01929-5
PMCID: PMC10005939

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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