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Article

Feasibility of pharmacogenetic-guided selection of postoperative analgesics in gynecologic surgery patients: a prospective, randomized, pilot study.

Pharmacogenetics and genomics - 1 Aug 2025

Hoffecker Glenda, Mulugeta-Gordon Lakeisha, Wittner Victoria, Wang Xingmei, Gysler Stefan, Deagostino-Kelly Mary, Tuteja Sony

Abstract excerpt

OBJECTIVES: Evaluate the feasibility of implementing a multigene pharmacogenetic (PGx) test and genotype-guided pharmacist recommendations into gynecologic perioperative workflows and fidelity to pharmacist genotype-guided postoperative analgesic recommendations. METHODS: A randomized, prospective, open-label pilot study was conducted in gynecologic patients undergoing abdominal surgery. Participants received...

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PMID: 40327052
DOI: 10.1097/FPC.0000000000000568

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