Article
Opportunity for Genotype-Guided Prescribing Among Adult Patients in 11 US Health Systems.
Clinical pharmacology and therapeutics - 1 Jul 2021
Hicks J Kevin, El Rouby Nihal, Ong Henry H, Schildcrout Jonathan S, Ramsey Laura B, Shi Yaping, Anne Tang Leigh, Aquilante Christina L, Beitelshees Amber L, Blake Kathryn V, Cimino James J, Davis Brittney H, Empey Philip E, Kao David P, Lemkin Daniel L, Limdi Nita A, P Lipori Gloria, Rosenman Marc B, Skaar Todd C, Teal Evgenia, Tuteja Sony, Wiley Laura K, Williams Helen, Winterstein Almut G, Van Driest Sara L, Cavallari Larisa H, Peterson Josh F
Abstract excerpt
The value of utilizing a multigene pharmacogenetic panel to tailor pharmacotherapy is contingent on the prevalence of prescribed medications with an actionable pharmacogenetic association. The Clinical Pharmacogenetics Implementation Consortium (CPIC) has categorized over 35 gene-drug pairs as "level A," for which there is sufficiently strong evidence to recommend that genetic information be used to guide drug...
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