Back to search

Article

Circadian clock-related genome-wide Mendelian randomization identifies putatively genes for ulcerative colitis and its comorbidity

2023-09-01

Abstract excerpt

<h4>Background: </h4> Circadian rhythm is crucial to the function of the immune system. Disorders of the circadian rhythm can lead to inflammatory diseases such as UC. This Mendelian Randomization (MR) analysis applies genetic tools to represent the aggregated statistical results of exposure to circadian rhythm disorders and UC and its comorbidities, allowing for causal inferences. <h4>Methods: </h4> Summary stat...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
17f9f3dc-998a-5c43-a45a-6413b7bee145
DOI
10.21203/rs.3.rs-3292704/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Circadian clock-related genome-wide Mendelian randomization identifies putatively genes for ulcerative colitis and its comorbidityDOI 10.21203/rs.3.rs-3292704/v1
Identification of circadian rhythm-related genes in colorectal cancer by integrating bioinformatics and multi-omics mendelian randomization.Semantic proximity
Mendelian randomization analysis of psoriasis and psoriatic arthritis associated with risks of ulcerative colitis.Semantic proximity
Elucidating the genetic relationship between ulcerative colitis and diabetic kidney disease: a bidirectional Mendelian randomization study.Semantic proximity
Mendelian Randomization Identifies Putative Aging-Related Causal Genes With Diagnostic Potential in Ulcerative Colitis.Semantic proximity
Causal linkage between type 2 diabetes mellitus and inflammatory bowel disease: an integrated Mendelian randomization study and bioinformatics analysisSemantic proximity
Mendelian Disease Associations Reveal Novel Insights into Inflammatory Bowel Disease.Semantic proximity
Causal Association of Inflammatory Bowel Disease on Anorexia Nervosa: A Two-sample Mendelian Randomization StudySemantic proximity
Circadian Clock Genes Are Correlated with Prognosis and Immune Cell Infiltration in Colon Adenocarcinoma.Semantic proximity
Circadian clock gene polymorphisms implicated in human pathologies.Semantic proximity
Global and regional genetic association analysis of ulcerative colitis and type 2 diabetes mellitus and causal validation analysis of two-sample two-way Mendelian randomization.Semantic proximity
Circadian Regulator PER2 Protects Against Epithelial Necroptosis in Ulcerative Colitis via the STAT1–ZBP1 AxisSemantic proximity
Endoplasmic reticulum stress related genome-wide Mendelian randomization identifies therapeutic genes for ulcerative colitis and Crohn’s diseaseSemantic proximity
Select a neighboring publication to make it the new centre.